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Premature ejaculation (PE), also known as rapid ejaculation, premature
climax, early ejaculation, or by the Latin term ejaculatio praecox, is the most
common sexual problem in men, affecting 25%-40% of men. It is characterized by a
lack of voluntary control over ejaculation. Masters and Johnson stated that a
man suffers from premature ejaculation if he ejaculates before his partner
achieves orgasm in more than fifty percent of his sexual encounters. Other sex
researchers have defined premature ejaculation as occurring if the man
ejaculates within two minutes or less of penetration; however, a survey by
Alfred Kinsey in the 1950s demonstrated that three quarters of men ejaculated
within two minutes of penetration in over half of their sexual encounters.
Today, most sex therapists understand premature ejaculation as occurring when a
lack of ejaculatory control interferes with sexual or emotional well-being in
one or both partners. Masters and Johnson recommended the use of the lateral
coital position to help alleviate premature ejaculation.
Most men experience premature ejaculation at least once in their lives. Often
adolescents and young men experience "premature" ejaculation during their first
sexual encounters, but eventually learn ejaculatory control. Because there is
great variability in both how long it takes men to ejaculate and how long both
partners want sex to last, researchers have begun to form a quantitative
definition of premature ejaculation. Current evidence supports an average
intravaginal ejaculation latency time (IELT) of six and a half minutes in 18-30
year olds.[1] If the disorder is defined as an IELT percentile below 2.5, then
premature ejaculation could be suggested by an IELT of less than about one and a
half minutes. Nevertheless, it is well accepted that men with IELTs below 1.5
minutes could be "happy" with their performance and do not report a lack of
control and therefore do not suffer from PE. On the other hand, a man with 2
minutes IELT could present with perception of poor control over his ejaculation,
distressed about his condition, has interpersonal difficulties and therefore be
diagnosed with PE.
Scientists have long suspected a genetic link to certain forms of premature
ejaculation. In one study, ninety-one percent of men who suffered from lifelong
premature ejaculation also had a first-relative with lifelong premature
ejaculation. Other researchers have noted that men who suffer from premature
ejaculation have a faster neurological response in the pelvic muscles. Simple
exercises commonly suggested by sex therapists can significantly improve
ejaculatory control for men with premature ejaculation caused by neurological
factors. Often, these men may benefit from anti-anxiety
medication or selective serotonin reuptake inhibitors (SSRIs), such as
sertraline or paroxetine. Some men prefer using anesthetic creams; however,
these creams may also deaden sensations in the man's partner, and are not
generally recommended by sex therapists.
Psychological factors also commonly contribute to premature ejaculation. While
men sometimes underestimate the relationship between sexual performance and
emotional well-being, premature ejaculation can be caused by temporary
depression, stress over financial matters, unrealistic expectations about
performance, a history of sexual repression, or an overall lack of confidence.
Interpersonal dynamics strongly contribute to sexual function, and premature
ejaculation can be caused by a lack of communication between partners, hurt
feelings, or unresolved conflicts that interfere with the ability to achieve
emotional intimacy. Neurological premature ejaculation can also lead to other
forms of sexual dysfunction, or intensify the existing problem, by creating
performance anxiety. In a less pathological context, premature ejaculation could
also be simply caused by extreme arousal.
Some physical illnesses, such as a prostate infection, are also known to induce
premature ejaculation. In other instances, premature ejaculation is caused by a
physical injury that affects the nervous system. Certain medications, such as
cold medications containing pseudoephedrine, also cause premature ejaculation.
Sexual dysfunction is a common symptom of psychiatric afflictions ranging from
bipolar disorder to post-traumatic stress disorder. In these cases, it is best
to discuss the issues openly with a physician.
Today it is believed that the neurotransmitor serotonin (5HT) has a central role
in modulating ejaculation. Several animal studies have demostrated its
inhibitory effect on ejaculation modulated through the PGI system in the brain.
Therefore, it is perceived that low level of serotonin in the synaptic cleft in
these specific areas in the brain could cause premature ejaculation. This theory
is further supported by the proven effectiveness of SSRIs, which increase
serotonin level in the synapse, in treating PE.
Treatment
Depending on severity, premature ejaculation symptoms can be significantly
reduced. In mundane cases, treatments are focused on gradually training and
improving mental habituation to sex and physical development of stimulation
control. In clinical cases, various medications are being trialled to help slow
down the speed of the arousal response.
SSRI antidepressants have been shown to delay ejaculation in men treated for
different psychiatry disorders. SSRIs are considered the most effective
treatment currently available for PE. These include paroxetine, fluoxetine,
sertraline and more. The use of these drugs, that require chronic therapy is
limited by the neuropsychiatric side effects. New SSRI drugs specifically
targeted to treat premature ejaculation (e.g. dapoxetine) can be taken on an as
needed basis and have been recently shown positive results in large phase III
studies. Nevertheless dapoxetine is not yet approved by any regulatory authority
around the world. There is speculation that some of the associated effects are
caused by lowered libido and blood pressure as well as lowered anxiety levels.
Other pharmaceutical products known to delay male orgasm are; opioids, cocaine,
and diphenhydramine.
Local anesthetic creams (like lidocaine, prilocaine and combinations) have shown
to be very effective in clinical trials and are being used of the treatment of
PE. Their use is limited by its own anesthetic effect that reduce sensation on
the penis and vagina.
Most sex therapists prescribe a series of exercises to enable the man to gain
ejaculatory control. While the exercises are intended for men who suffer from
premature ejaculation, other men can use the exercises to enhance their sex
lives. By far the most common exercise is the so-called start-stop technique.
While the technique varies, the purpose is to get the male accustomed to
maintaining an erection for an extended period of time while gradually
increasing sexual tolerance. In doing this exercise, the male obtains an
erection through self-stimulation, or masturbation. After achieving an erection,
he stops stimulating himself until he begins to lose his erection; at that
point, he begins to stimulate himself again. Gradually, over a period of several
weeks, he is able to stimulate himself for longer periods of time, eventually
gaining ejaculatory control. In order for this technique to be successful, the
male should avoid feeling discouraged if he ejaculates rapidly; instead, he
should use his sexual responses to learn how to vary the technique in a way that
most benefits him. Another variant, for example, is to stimulate the shaft and
frenulum of the penis, exploring the glans more as control improves.
The male's partner is usually integrated into the exercises. They can stimulate
the partner using the stop-start technique. When the male has achieved some
level of ejaculatory control, he can insert his penis into his partner without
thrusting. After his penis becomes accustomed to being inside his partner,
thrusting can be gradually included, according to the male's abilities, using
the stop-start technique. In less severe cases, the male might overcome his
premature ejaculation early on, making exercises with his partner superfluous.
The male's partner plays an essential role in enabling him to overcome premature
ejaculation. Without understanding and emotional support, the male is unlikely
to obtain the level of relaxation required for sexual satisfaction. Both the
male and his partner should communicate their feelings openly and with
sensitivity. The male should learn to sexually satisfy his partner, orally or
otherwise, while they work with him to overcome his premature ejaculation.
External latex rigid sheathes fastened to the body have been developed that
cover all part of the penis during penetration so that the penis is protected
from all the stimulation of the vagina. These help to gain control and to
provide satisfaction to the partner.
Diagnosis
Diagnostic criteria for Premature Ejaculation from the DSM-IV (American Psychiatric
Association)
- Persistent or recurrent ejaculation with minimal sexual stimulation before,
on, or shortly after penetration and before the person wishes it. The clinician
must take into account factors that affect duration of the excitement phase,
such as age, novelty of the sexual partner or situation, and recent frequency of
sexual activity.
- The disturbance causes marked distress or interpersonal difficulty.
- The premature ejaculation is not due exclusively to the direct effects of a
substance (e.g., withdrawal from opioids).
Differential diagnosis
Premature ejaculation should be distinguished from erectile dysfunction related
to the development of a general medical condition. Some individuals with
erectile dysfunction may omit their usual strategies for delaying orgasm. Others
require prolonged noncoital stimulation to develop a degree of erection
sufficient for intromission. In such individuals, sexual arousal may be so high
that ejaculation occurs immediately. Occasional problems with premature
ejaculation that are not persistent or recurrent or are not accompanied by
marked distress or interpersonal difficulty do not qualify for the diagnosis of
premature ejaculation. The clinician should also take into account the
individual's age, overall sexual experience, recent sexual activity, and the
novelty of the partner. When problems with premature ejaculation are due
exclusively to substance use (e.g., opiate withdrawal), a substance-induced
sexual dysfunction can be diagnosed.
Sources
DSM-IV (American Psychological Association)
Centers for Disease Control
National Institutes of Health
Wikipedia

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